Article
Low prevalence of BRCA1 and BRCA2 mutations in the sporadic breast cancer of Spanish population.
Familial cancer - 1 Mar 2012
de Juan Jiménez Inmaculada, Esteban Cardeñosa Eva, Palanca Suela Sarai, Barragán González Eva, Aznar Carretero Ismael, Munárriz Gandía Blanca, Santaballa Bertran Ana, Torregrosa Maicas María Dolores, Guillén Ponce Carmen, Sánchez Heras Ana Beatriz, Bayón Lara Ana, Fuster Lluch Oscar, Bolufer Gilabert Pascual
Abstract excerpt
The true prevalence of BRCA1/BRCA2 (BRCAs) germline mutations in sporadic breast or ovarian cancer (SBC/SOC) in Caucasian population is not well established. The aim of the study is to establish the prevalence of BRCAs mutations in SBC to ponder its relevance in the programs of genetic counseling in cancer and to explore the genotype-phenotype relationship of these particular breast cancers. The study was...
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