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Germline mutations of BRCA1 and BRCA2 in Korean sporadic ovarian carcinoma.

Gynecologic oncology - 1 Dec 2005

Kim Young Tae, Nam Eun Ji, Yoon Bo Sung, Kim Sang Wun, Kim Sung Hoon, Kim Jae Hoon, Kim Hyun Ki, Koo Ja Seong, Kim Jae Wook

Abstract excerpt

OBJECTIVES: Mutations in the BRCA1 and BRCA2 genes predispose women to ovarian and/or breast cancer. The contribution of BRCA1 and BRCA2 mutations to ovarian cancer in Korean women remains to be elucidated. In addition, genetic polymorphisms may affect not only cancer development but also cancer progression and, as a result, could influence cancer phenotypes. The purposes of this study were, first, to investigate...

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Topics

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 16084575
DOI: 10.1016/j.ygyno.2005.06.058

Genes

BRCA1
BRCA2

Provenance

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