Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Molecular Characterization of the Tumor-Suppressive Function of Nischarin in Breast Cancer

14 Sept 2011

Abstract excerpt

BACKGROUND: Nischarin (encoded by NISCH), an α5 integrin-binding protein, has been identified as a regulator of breast cancer cell invasion. We hypothesized that it might be a tumor suppressor and were interested in its regulation. METHODS: We examined nischarin expression in approximately 300 human breast cancer and normal tissues using quantitative polymerase chain reaction and immunohistochemistry. Loss of...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cell Adhesion Molecules Research
Share to Proteoglycans and glycosaminoglycans research
Share to Wnt/β-catenin signaling in development and cancer

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 21917605
DOI: 10.1093/jnci/djr350

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Molecular Characterization of the Tumor-Suppressive Function of Nischarin in Breast CancerPMID 21917605Read ↗

Pan-cancer analysis reveals that nischarin may not be the universal tumor suppressorSemantic proximity Read ↗

Nischarin expression may have differing roles in male and female melanoma patientsSemantic proximity Read ↗

SNHG14 promotes triple‐negative breast cancer cell proliferation, invasion, and chemoresistance by regulating the ERK / MAPK signaling pathwaySemantic proximity Read ↗

Truncated RON Tyrosine Kinase Drives Tumor Cell Progression and Abrogates Cell-Cell Adhesion Through E-Cadherin Transcriptional RepressionSemantic proximity Read ↗

Synaptojanin 2 is a druggable mediator of metastasis and the gene is overexpressed and amplified in breast cancerSemantic proximity Read ↗

Oncogenesis of RON receptor tyrosine kinase: a molecular target for malignant epithelial cancers.Semantic proximity Read ↗

Integrin β4 Regulates SPARC Protein to Promote InvasionSemantic proximity Read ↗

Suppression of Spry1 inhibits triple-negative breast cancer malignancy by decreasing EGF/EGFR mediated mesenchymal phenotypeSemantic proximity Read ↗

Sorting nexin 9 negatively regulates invadopodia formation and function in cancer cellsSemantic proximity Read ↗

Nodal promotes invasive phenotypes via a mitogen-activated protein kinase-dependent pathway.Semantic proximity Read ↗

NCSTN promotes hepatocellular carcinoma cell growth and metastasis via β-catenin activation in a Notch1/AKT dependent mannerSemantic proximity Read ↗

Role of Nischarin in the pathology of diseases: a special emphasis on breast cancerSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.