Article

Pan-cancer analysis reveals that nischarin may not be the universal tumor suppressor

2022-11-22

Abstract excerpt

<title>Abstract</title> <p><bold>Background: </bold>Scaffolding protein nischarin (NISCH) was reported to be a tumor suppressor that plays a critical role in breast cancer initiation and progression through regulation of the cytoskeleton dynamics. NISCH expression was reported to be a positive prognostic marker in breast, ovarian and lung cancers. Our group has found that in melanoma, NISCH had positive prognosti...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 9c726d6f-c780-5242-9dce-bee308f812dc
DOI: 10.21203/rs.3.rs-2288348/v1

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Pan-cancer analysis reveals that nischarin may not be the universal tumor suppressorDOI 10.21203/rs.3.rs-2288348/v1Read

Nischarin expression may have differing roles in male and female melanoma patientsSemantic proximity Read

Molecular Characterization of the Tumor-Suppressive Function of Nischarin in Breast CancerSemantic proximity Read

Bioinformatic analysis of SEMA4D and its potential clinical value research in pan-cancerSemantic proximity Read

SNHG14 promotes triple‐negative breast cancer cell proliferation, invasion, and chemoresistance by regulating the ERK / MAPK signaling pathwaySemantic proximity Read

A Pan-Cancer Analysis of FAT Atypical Cadherin 4 (FAT4) in Human TumorsSemantic proximity Read

Menin in CancerSemantic proximity Read

KNSTRN Is a Prognostic Biomarker That Is Correlated with Immune Infiltration in Breast Cancer and Promotes Cell Cycle and ProliferationSemantic proximity Read

Characterization of a Novel MAP4K4-SASH1 Kinase Cascade Regulating Breast Cancer Tumorigenesis and MetastasisSemantic proximity Read

Role of Nischarin in the pathology of diseases: a special emphasis on breast cancerSemantic proximity Read

Highly expressed NRSN2 is related to malignant phenotype in ovarian cancer.Semantic proximity Read

Integrated analysis unraveling the immunologic and clinical prognostic values of Synaptotagmin Like 4 in pan-cancerSemantic proximity Read

Stathmin1 regulates p27 expression, proliferation and drug resistance, resulting in poor clinical prognosis in cholangiocarcinomaSemantic proximity Read