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Article

Role of TLRs and IL-6 in the outcome of chronic hepatitis C treatment in Tunisian population.

Cytokine - 1 Nov 2017

Sghaier Ikram, Mouelhi Leila, Ghazoueni Ezzedine, Brochot Etienne, Almawi Wassim Y, Yacoubi-Loueslati Besma

Abstract excerpt

OBJECTIVES: TLRs are one of the most studied families of pathogen recognition receptors (PRRs) and play a pivotal role during HCV infection. The binding of ligands to TLRs on antigen presenting cells (APCs) leads to secretion of inflammatory cytokines, such as IL6, and induction of the acquired immunity response. Therefore, it has become necessarily to harness the TLRs properties' on therapeutically tools to...

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PMID: 28823914
DOI: 10.1016/j.cyto.2017.08.010

Genes

TLR3
TLR4

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