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Article

Evolution of hepatitis B virus during long-term therapy in patients with chronic hepatitis B.

Annals of hepatology - 1 Jan 2000

Arrese Elisabete, Basaras Miren, Blanco Sonia, Ruiz Pablo, Cisterna Ramón

Abstract excerpt

BACKGROUND: Long-term lamivudine (LAM), adefovir (ADV) and entecavir (ETV) treatment induce the emergence of drug-resistant hepatitis B virus (HBV) in patients with chronic hepatitis B infection. AIM: To evaluate the LAM, ADV and ETV resistance mutations detected in our patient group. MATERIALS AND METHODS: Twenty patients who had received at least two years of treatment with nucleoside/tide analogues were...

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PMID: 21911882

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

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