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CID12261165, a flavonoid compound as antibacterial agents against quinolone-resistant Staphylococcus aureus

31 Jan 2023

Abstract excerpt

Flavonoids are plant-produced secondary metabolites that are found ubiquitously. We have previously reported that apigenin, a class of flavonoid, has unique antimicrobial activity against Staphylococcus aureus (S. aureus), one of the major human pathogens. Apigenin inhibited fluoroquinolone-resistant S. aureus with DNA gyrase harboring the quinolone-resistant S84L mutation but did not inhibit wild-type DNA...

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PMID: 36720958
DOI: 10.1038/s41598-023-28859-8

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