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Article

A genetic variant at the fatty acid-binding protein aP2 locus reduces the risk for hypertriglyceridemia, type 2 diabetes, and cardiovascular disease.

Proceedings of the National Academy of Sciences of the United States of America - 2 May 2006

Tuncman G, Erbay E, Hom X, De Vivo I, Campos H, Rimm E B, Hotamisligil G S

Abstract excerpt

Obesity and the associated pathologies including dyslipidemia, insulin resistance, type 2 diabetes, and cardiovascular disease constitute a major threat to global human health. Yet, the genetic factors that differentially predispose individuals to this cluster of pathologies are unclear. The fatty acid-binding protein aP2 is a cytoplasmic lipid chaperon expressed in adipocytes and macrophages. Mice with aP2...

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Identifiers

PMID: 16641093
DOI: 10.1073/pnas.0602178103
PMCID: PMC1447594

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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