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Article

Association of OLR1 gene polymorphisms with the risk of coronary artery disease: A systematic review and meta-analysis.

Heart & lung : the journal of critical care - 1 Jan 2000

Salehipour Pouya, Rezagholizadeh Farzaneh, Mahdiannasser Mojdeh, Kazerani Reihane, Modarressi Mohammad Hossein

Abstract excerpt

BACKGROUND: Oxidized LDL receptor 1 (OLR1) encodes LOX-1, LOXIN, and OLR1D4 transcript variants. Up-regulation of LOX-1 and down-regulation of LOXIN have an essential role in causing coronary artery disease (CAD). Discovery of risk single nucleotide polymorphisms (SNPs) in OLR1 gene is clinically important as these polymorphisms could be candidate biomarkers of CAD. OBJECTIVES: The purpose of this study is...

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Identifiers

PMID: 33524863
DOI: 10.1016/j.hrtlng.2021.01.015

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