Article
Expression of interleukin-15 and interleukin-15Rα in monocytes of HIV type 1-infected patients with different courses of disease progression.
AIDS research and human retroviruses - 1 Jul 2012
Tarkowski Maciej, Ferraris Laurenzia, Martone Sara, Strambio de Castillia Francesco, Misciagna Donatella, Mazzucchelli Renata I, Lattuada Emanuela, Paraninfo Giuseppe, Galli Massimo, Riva Agostino
Abstract excerpt
Interleukin-15 (IL-15) enhances the effector mechanisms of anti-HIV immune responses and thus is considered a potential adjuvant of HIV-1 vaccine. However, there are a lack of data concerning the relationships between IL-15 expression and regulation in HIV-1-infected patients and the course of disease progression. We found that IL-15, but not IL-15Rα, is expressed at significantly higher levels in the CD14(+)...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
