Article
The genetics of cutaneous melanoma.
Clinics in laboratory medicine - 1 Dec 2000
Pollock P M, Trent J M
Abstract excerpt
Although germline mutations in CDKN2A are present in approximately 25% of large multicase melanoma families, germline mutations are much rarer in the smaller melanoma families that make up most individuals reporting a family history of this disease. In addition, only three families worldwide have been reported with germline mutations in a gene other than CDKN2A (i.e., CDK4). Accordingly, current genomewide scans...
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