Article
[Identification of risk genes for myocardial infarction by genome wide association studies].
Hamostaseologie - 1 Nov 2010
Linsel-Nitschke P, Erdmann J, Schunkert H
Abstract excerpt
Myocardial infarction (MI) shows a strong heritability. For a long time the identification of responsible genes has been rather unsuccessful. However, with the advent of genome wide association studies (GWAS) using DNA-array technology a number of significant loci for MI have been identified which were widely replicated. Interestingly, only a small fraction of the hitherto identified genes is also associated with...
Topics
- Chromosome Mapping
- Chromosomes, Human
- Gene Expression Profiling
- Genetic Variation
- Genome-Wide Association Study
- Hemostasis
- Humans
- Myocardial Infarction
- Oligonucleotide Array Sequence Analysis
- Polymorphism, Single Nucleotide
- Risk Assessment
