Article
Genome-wide detection of allele specific copy number variation associated with insulin resistance in African Americans from the HyperGEN study.
PloS one - 1 Jan 2011
Irvin Marguerite R, Wineinger Nathan E, Rice Treva K, Pajewski Nicholas M, Kabagambe Edmond K, Gu Charles C, Pankow Jim, North Kari E, Wilk Jemma B, Freedman Barry I, Franceschini Nora, Broeckel Uli, Tiwari Hemant K, Arnett Donna K
Abstract excerpt
African Americans have been understudied in genome wide association studies of diabetes and related traits. In the current study, we examined the joint association of single nucleotide polymorphisms (SNPs) and copy number variants (CNVs) with fasting insulin and an index of insulin resistance (HOMA-IR) in the HyperGEN study, a family based study with proband ascertainment for hypertension. This analysis is...
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