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Article

Proteomic analysis of oligodendrogliomas expressing a mutant isocitrate dehydrogenase-1.

Proteomics - 1 Nov 2011

Thirant Cécile, Varlet Pascale, Lipecka Joanna, Le Gall Morgane, Broussard Cédric, Chafey Philippe, Studler Jeanne-Marie, Lacombe Joelle, Lions Séverin, Guillaudeau Angélique, Camoin Luc, Daumas-Duport Catherine, Junier Marie-Pierre, Chneiweiss Hervé

Abstract excerpt

Gliomas are primary tumors of the human central nervous system with unknown mechanisms of progression. Isocitrate dehydrogenase-1 (IDH1) mutation is frequent in diffuse gliomas such as oligodendrogliomas. To gain insights into the physiopathology of oligodendrogliomas that have a better prognosis than other diffuse gliomas, we combined microdissection, 2-D DIGE and MS/MS focusing on proteome alterations...

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Source

Identifiers

PMID: 21898821
DOI: 10.1002/pmic.201000646

Genes

IDH1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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