Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Genetic Interactions Between Hepatocyte Nuclear Factor–6 and Notch Signaling Regulate Mouse Intrahepatic Bile Duct Development in Vivo

31 Aug 2011

Abstract excerpt

UNLABELLED: Notch signaling and hepatocyte nuclear factor-6 (HNF-6) are two genetic factors known to affect lineage commitment in the bipotential hepatoblast progenitor cell (BHPC) population. A genetic interaction involving Notch signaling and HNF-6 in mice has been inferred through separate experiments showing that both affect BHPC specification and bile duct morphogenesis. To define the genetic interaction...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Liver physiology and pathology
Share to Organ Transplantation Techniques and Outcomes
Share to Pancreatic function and diabetes

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 21898486
DOI: 10.1002/hep.24631

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Genetic Interactions Between Hepatocyte Nuclear Factor–6 and Notch Signaling Regulate Mouse Intrahepatic Bile Duct Development in VivoPMID 21898486Read ↗

The onecut transcription factor HNF6 is required for normal development of the biliary tractSemantic proximity Read ↗

The Transcription Factor Hepatocyte Nuclear Factor-6 Controls the Development of Pancreatic Ducts in the MouseSemantic proximity Read ↗

Notch Signaling Coordinates Progenitor Cell-Mediated Biliary Regeneration Following Partial HepatectomySemantic proximity Read ↗

A classification of ductal plate malformations based on distinct pathogenic mechanisms of biliary dysmorphogenesisSemantic proximity Read ↗

Notch signaling controls liver development by regulating biliary differentiationSemantic proximity Read ↗

Liver‐specific inactivation of Notch2, but not Notch1, compromises intrahepatic bile duct development in mice†‡Semantic proximity Read ↗

YAP Activation Drives Liver Regeneration after Cholestatic Damage Induced by Rbpj DeletionSemantic proximity Read ↗

Suppression of C/EBPα expression in periportal hepatoblasts may stimulate biliary cell differentiation through increased<i>Hnf6</i>and<i>Hnf1b</i>expressionSemantic proximity Read ↗

Identification of the bHLH Factor Math6 as a Novel Component of the Embryonic Pancreas Transcriptional NetworkSemantic proximity Read ↗

The zebrafish onecut gene hnf-6 functions in an evolutionarily conserved genetic pathway that regulates vertebrate biliary developmentSemantic proximity Read ↗

Hepatocyte nuclear factor 1α and β control terminal differentiation and cell fate commitment in the gut epitheliumSemantic proximity Read ↗

Sox9 Is a Modifier of the Liver Disease Severity in a Mouse Model of Alagille SyndromeSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.