Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Suppression of C/EBPα expression in periportal hepatoblasts may stimulate biliary cell differentiation through increased<i>Hnf6</i>and<i>Hnf1b</i>expression

5 Oct 2006

Abstract excerpt

The expression of C/EBPalpha, which may govern transcription of mature hepatocyte marker genes, was suppressed in periportal hepatoblasts in mouse liver development, leading to biliary cell differentiation. This study was undertaken to analyze how inactivation of the Cebpa gene affects biliary cell differentiation and gene expression of the regulatory genes for that differentiation, including Hnf1b and Hnf6. In...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Genetics and Neurodevelopmental Disorders
Share to Liver physiology and pathology
Share to Pediatric Hepatobiliary Diseases and Treatments

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 17021047
DOI: 10.1242/dev.02591

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 3 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Suppression of C/EBPα expression in periportal hepatoblasts may stimulate biliary cell differentiation through increased<i>Hnf6</i>and<i>Hnf1b</i>expressionPMID 17021047Read ↗

Suppression of C/EBP α expression in biliary cell differentiation from hepatoblasts during mouse liver developmentSemantic proximity Read ↗

The onecut transcription factor HNF6 is required for normal development of the biliary tractSemantic proximity Read ↗

A classification of ductal plate malformations based on distinct pathogenic mechanisms of biliary dysmorphogenesisSemantic proximity Read ↗

Increased hepatic cell proliferation and lung abnormalities in mice deficient in CCAAT/enhancer binding protein alpha.Semantic proximity Read ↗

Notch Signaling Coordinates Progenitor Cell-Mediated Biliary Regeneration Following Partial HepatectomySemantic proximity Read ↗

Genetic Interactions Between Hepatocyte Nuclear Factor–6 and Notch Signaling Regulate Mouse Intrahepatic Bile Duct Development in VivoSemantic proximity Read ↗

Prox1 ablation in hepatic progenitors causes defective hepatocyte specification and increases biliary cell commitmentSemantic proximity Read ↗

CCAAT/enhancer binding protein alpha knock-in mice exhibit early liver glycogen storage and reduced susceptibility to hepatocellular carcinoma.Semantic proximity Read ↗

Notch signaling controls hepatoblast differentiation by altering the expression of liver-enriched transcription factorsSemantic proximity Read ↗

Transcription Factor Hepatocyte Nuclear Factor 6 Regulates Pancreatic Endocrine Cell Differentiation and Controls Expression of the Proendocrine Gene <i>ngn3</i>Semantic proximity Read ↗

Regulation of Liver Regeneration by hepatocyte O-GlcNAcylation in miceSemantic proximity Read ↗

Bile system morphogenesis defects and liver dysfunction upon targeted deletion of HNF1beta.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.