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Article

FUdR causes a twofold increase in the lifespan of the mitochondrial mutant gas-1.

Mechanisms of ageing and development - 1 Oct 2011

Van Raamsdonk Jeremy Michael, Hekimi Siegfried

Abstract excerpt

The nematode worm Caenorhabditis elegans has been used to identify hundreds of genes that influence longevity and thereby demonstrate the strong influence of genetics on lifespan determination. In order to simplify lifespan studies in worms, many researchers have employed 5-fluoro-2'-deoxyuridine (FUdR) to inhibit the development of progeny. While FUdR has little impact on the lifespan of wild-type worms, we...

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Identifiers

PMID: 21893079
DOI: 10.1016/j.mad.2011.08.006
PMCID: PMC4074524

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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