Article
Genetic variability in N-acetyltransferase 2 gene determines susceptibility to childhood lymphoid or myeloid leukemia in Brazil.
Leukemia & lymphoma - 1 Feb 2012
Zanrosso Crisiane Wais, Emerenciano Mariana, Faro Alessandra, Gonçalves Bruno Alves De Aguiar, Mansur Marcela Braga, Pombo-de-Oliveira Maria S
Abstract excerpt
Seven single nucleotide polymorphisms (SNPs) were genotyped in 535 Brazilian children (158 with acute lymphoblastic leukemia [ALL], 74 with acute myeloid leukemia [AML] and 303 controls). The subjects were classified as fast or slow acetylators based on their genotypic variants. Logistic regression was used to estimate odds ratios (ORs) and 95% confidence intervals. N-acetyltransferase 2 (NAT2) SNP 341T > C...
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