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Article

Pathway analysis of genetic markers associated with a functional MRI faces paradigm implicates polymorphisms in calcium responsive pathways.

NeuroImage - 15 Apr 2013

Mattingsdal Morten, Brown Andrew Anand, Djurovic Srdjan, Sønderby Ida Elken, Server Andres, Melle Ingrid, Agartz Ingrid, Hovig Eivind, Jensen Jimmy, Andreassen Ole A

Abstract excerpt

Several lines of evidence suggest that common polygenic variation influences brain function in humans. Combining high-density genetic markers with brain imaging techniques is constricted by the practicalities of collecting sufficiently large brain imaging samples. Pathway analysis promises to leverage knowledge on function of genes to detect recurring signals of moderate effect. We adapt this approach, exploiting...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 23274185
DOI: 10.1016/j.neuroimage.2012.12.035

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RASGRF2

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