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Article

Helicobacter pylori arginase mutant colonizes arginase II knockout mice.

World journal of gastroenterology - 28 Jul 2011

Kim Songhee H, Langford Melanie L, Boucher Jean-Luc, Testerman Traci L, McGee David J

Abstract excerpt

AIM: To investigate the role of host and bacterial arginases in the colonization of mice by Helicobacter pylori (H. pylori). METHODS: H. pylori produces a very powerful urease that hydrolyzes urea to carbon dioxide and ammonium, which neutralizes acid. Urease is absolutely essential to H. pylori pathogenesis; therefore, the urea substrate must be in ample supply for urease to work efficiently. The urea substrate...

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Identifiers

PMID: 21876618
DOI: 10.3748/wjg.v17.i28.3300
PMCID: PMC3160534

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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