Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Genes involved in stress response influence lithium efficacy in bipolar patients.

Bipolar disorders - 1 Dec 2018

Szczepankiewicz Aleksandra, Narozna Beata, Rybakowski Janusz K, Kliwicki Sebastian, Czerski Piotr, Dmitrzak-Węglarz Monika, Skibińska Maria, Twarowska-Hauser Joanna, Pawlak Joanna

Abstract excerpt

OBJECTIVES: In mood disorders, chronic stimulation with stress results in aberrant regulation of the hypothalamic-pituitary-adrenal (HPA) axis. Lithium was shown to influence HPA axis function. The underlying genetic background as well as environmental context may influence the stress response, and therefore lithium efficacy. The aim of the present study was to analyze if genetic variants located in genes...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Bipolar Disorder
Share to Gene Expression

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Haplotypes

Share to Hypothalamo-Hypophyseal System

Share to Linkage Disequilibrium

Share to Mood Disorders

Share to Pituitary-Adrenal System

Share to Stress, Psychological

Source

Identifiers

PMID: 29578315
DOI: 10.1111/bdi.12639

Genes

ACP1
FKBP5
BAG1
BCL2
CRHR1
DUSP1
FKBP4
SRSF5
SRSF9
STIP1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Genes involved in stress response influence lithium efficacy in bipolar patients.PMID 29578315Read ↗

Exploring the genetics of lithium response in bipolar disordersSemantic proximity Read ↗

The implication of ADRA2A and AVPRIB gene variants in the aetiology of stress-related bipolar disorder.Semantic proximity Read ↗

Glucocorticoid receptor polymorphism is associated with lithium response in bipolar patients.Semantic proximity Read ↗

Immunogenetics of lithium response and psychiatric phenotypes in patients with bipolar disorderSemantic proximity Read ↗

Lithium response and genetic variation in the CREB family of genes.Semantic proximity Read ↗

Lithium response in bipolar disorder: Genetics, genomics, and beyondSemantic proximity Read ↗

Advances in the pathophysiology of bipolar disorderSemantic proximity Read ↗

Differential Serum Levels of CACNA1C, Circadian Rhythm and Stress Response Molecules in Subjects with Bipolar Disorder: Associations with Genetic and Clinical FactorsSemantic proximity Read ↗

Genetic polymorphisms influencing response to lithium in early-onset Bipolar disorder from south India.Semantic proximity Read ↗

Exploring Genetic Variability at PI, GSK3, HPA, and Glutamatergic Pathways in Lithium Response: Association With IMPA2, INPP1, and GSK3B Genes.Semantic proximity Read ↗

Molecular Signatures of Lithium Treatment: Current KnowledgeSemantic proximity Read ↗

Pharmacogenomics of Lithium Response in Bipolar DisorderSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.