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Article

Next-generation computational genetic analysis: multiple complement alleles control survival after Candida albicans infection.

Infection and immunity - 1 Nov 2011

Peltz Gary, Zaas Aimee K, Zheng Ming, Solis Norma V, Zhang Mason X, Liu Hong-Hsing, Hu Yajing, Boxx Gayle M, Phan Quynh T, Dill David, Filler Scott G

Abstract excerpt

Candida albicans is a fungal pathogen that causes severe disseminated infections that can be lethal in immunocompromised patients. Genetic factors are known to alter the initial susceptibility to and severity of C. albicans infection. We developed a next-generation computational genetic mapping program with advanced features to identify genetic factors affecting survival in a murine genetic model of hematogenous...

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PMID: 21875959
DOI: 10.1128/IAI.05666-11
PMCID: PMC3257944

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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