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Article

CYP4A11 T8590C polymorphism, salt-sensitive hypertension, and renal blood flow.

Journal of hypertension - 1 Oct 2011

Williams Jonathan S, Hopkins Paul N, Jeunemaitre Xavier, Brown Nancy J

Abstract excerpt

OBJECTIVE AND METHODS: A loss-of-function cytosine (C) for thymidine (T) transition at nucleotide 8590 of CYP4A11 has been associated with increased blood pressure in humans. We tested the hypothesis that CYP4A11 T8590C genotype is associated with salt sensitivity in the International Hypertensive Pathotype cohort. RESULTS: CYP4A11 T8590C genotype was associated with hypertension in whites. Among normotensive...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 21873888
DOI: 10.1097/HJH.0b013e32834aa786
PMCID: PMC3309034

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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