Article
CACNA1D Gene Polymorphisms Associate With Increased Blood Pressure and Salt Sensitivity of Blood Pressure in White Individuals.
Hypertension (Dallas, Tex. : 1979) - 1 Dec 2023
Stanton Ana Maria, Heydarpour Mahyar, Williams Jonathan S, Williams Gordon H, Adler Gail K
Abstract excerpt
BACKGROUND: Disease-causing mutations in CACNA1D gene occur in aldosterone-producing adenomas and familial hyperaldosteronism. We determined whether single nucleotide polymorphisms in CACNA1D gene associate with higher aldosterone resulting in salt sensitivity of blood pressure (BP) and increased BP in men and women. METHODS: Data were obtained from the HyperPATH (International Hypertension Pathotypes) cohort,...
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