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Article

Novel advances in cytochrome P450 research.

Drug discovery today - 1 Sept 2011

Singh Deepika, Kashyap Akriti, Pandey Ram Vinay, Saini Kulvinder Singh

Abstract excerpt

The cytochrome P450 (CYP) enzymes, involved in the metabolism of therapeutic drugs, are the major determinants of drug half-life. From a drug industry perspective, variability in drug response owing to CYP polymorphisms makes CYP profiling a commercially interesting option for diagnosis, prognosis and predicting response to drug treatment. Recent studies highlighting microRNA-mediated regulation of CYP genes...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 21864709
DOI: 10.1016/j.drudis.2011.08.003

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