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Article

Lef1-dependent Wnt/β-catenin signalling drives the proliferative engine that maintains tissue homeostasis during lateral line development.

Development (Cambridge, England) - 1 Sept 2011

Valdivia Leonardo E, Young Rodrigo M, Hawkins Thomas A, Stickney Heather L, Cavodeassi Florencia, Schwarz Quenten, Pullin Lisa M, Villegas Rosario, Moro Enrico, Argenton Francesco, Allende Miguel L, Wilson Stephen W

Abstract excerpt

During tissue morphogenesis and differentiation, cells must self-renew while contemporaneously generating daughters that contribute to the growing tissue. How tissues achieve this precise balance between proliferation and differentiation is, in most instances, poorly understood. This is in part due to the difficulties in dissociating the mechanisms that underlie tissue patterning from those that regulate...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 21862557
DOI: 10.1242/dev.062695
PMCID: PMC3160090

Genes

PLLP

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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