Article
Statistical tests of selective neutrality in the age of genomics.
Heredity - 1 Jun 2001
Nielsen R
Abstract excerpt
Examining genomic data for traces of selection provides a powerful tool for identifying genomic regions of functional importance. Many methods for identifying such regions have focused on conserved sites. However, positive selection may also be an indication of functional importance. This article provides a brief review of some of the statistical methods used to detect selection using DNA sequence data or other...
Topics
- Alleles
- Animals
- Conserved Sequence
- Evolution, Molecular
- Gene Frequency
- Genetic Variation
- Genome
- Genomics
- Humans
- Models, Genetic
- Selection, Genetic
- Statistics as Topic
