Article
Mutation, selection and the future of human evolution.
Trends in genetics : TIG - 1 Sept 2006
Reed Floyd A, Aquadro Charles F
Abstract excerpt
Several recent analyses provide growing evidence of the influence of positive selection acting in the ancestors of modern humans. Additionally, the best way to explain current fluctuations in neutral variation across the genome is by including negative selection against a high rate of deleterious mutants. We suggest that explaining these predicted high deleterious mutation rates in humans could require the...
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