Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Topics Community

Article

Genetic susceptibility to chronic otitis media with effusion: candidate gene single nucleotide polymorphisms.

The Laryngoscope - 1 May 2014

MacArthur Carol J, Wilmot Beth, Wang Linda, Schuller Michael, Lighthall Jessyka, Trune Dennis

Abstract excerpt

OBJECTIVES/HYPOTHESIS: The genetic factors leading to a predisposition to otitis media are not well understood. The objective of the current study was to develop a tag-single nucleotide polymorphism (SNP) panel to determine if there is an association between candidate gene polymorphisms and the development of chronic otitis media with effusion. STUDY DESIGN: A 1:1 case/control design of 100 cases and 100 controls...

Topics

Adolescent
Case-Control Studies
Child
Child, Preschool
Chronic Disease
Female
Genetic Predisposition to Disease
Genotype
Humans
Infant
Male

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Mucin-5B

Otitis Media with Effusion

Phenotype

Polymorphism, Single Nucleotide

Risk Factors

Smad2 Protein

Smad4 Protein

Source

Open in PubMed Open full text

Identifiers

PMID: 23929584
DOI: 10.1002/lary.24349
PMCID: PMC3971016

Genes

TLR4
SMAD2
SMAD4

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026.

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

0

discussions

0

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Genetic susceptibility to chronic otitis media with effusion: candidate gene single nucleotide polymorphisms.PMID 23929584Read ↗

Genetic susceptibility to otitis media in childhood.Semantic proximity Read ↗

Evaluation of 15 functional candidate genes for association with chronic otitis media with effusion and/or recurrent otitis media (COME/ROM).Semantic proximity Read ↗

Panel 3: Genetics and Precision Medicine of Otitis Media.Semantic proximity Read ↗

Genetic background and the risk of otitis media.Semantic proximity Read ↗

Predisposition to Childhood Otitis Media and Genetic Polymorphisms within the Toll-Like Receptor 4 (TLR4) Locus.Semantic proximity Read ↗

Innate immunity gene single nucleotide polymorphisms and otitis media.Semantic proximity Read ↗

Genetic Polymorphisms of Functional Candidate Genes and Recurrent Acute Otitis Media With or Without Tympanic Membrane Perforation.Semantic proximity Read ↗

A genome-wide association study of chronic otitis media with effusion and recurrent otitis media identifies a novel susceptibility locus on chromosome 2.Semantic proximity Read ↗

Genome-wide association study to identify the genetic determinants of otitis media susceptibility in childhood.Semantic proximity Read ↗

Current Understanding of Host Genetics of Otitis MediaSemantic proximity Read ↗

A meta-analysis on genetic susceptibility to chronic otitis mediaSemantic proximity Read ↗

Immunity genes and susceptibility to otitis media: a comprehensive review.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.