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Article

Genetic susceptibility to chronic otitis media with effusion: candidate gene single nucleotide polymorphisms.

The Laryngoscope - 1 May 2014

MacArthur Carol J, Wilmot Beth, Wang Linda, Schuller Michael, Lighthall Jessyka, Trune Dennis

Abstract excerpt

OBJECTIVES/HYPOTHESIS: The genetic factors leading to a predisposition to otitis media are not well understood. The objective of the current study was to develop a tag-single nucleotide polymorphism (SNP) panel to determine if there is an association between candidate gene polymorphisms and the development of chronic otitis media with effusion. STUDY DESIGN: A 1:1 case/control design of 100 cases and 100 controls...

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Identifiers

PMID: 23929584
DOI: 10.1002/lary.24349
PMCID: PMC3971016

Genes

TLR4
SMAD2
SMAD4

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Source receipt: pubmed, retrieved 7 Sept 2026.

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