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Article

Genome-wide association study indicates novel associations of annexin A13 to secretory and GAS2L2 with mucous otitis media.

Scientific reports - 7 Aug 2024

Bizaki-Vallaskangas Argyro, Rämö Joel, Sliz Eeva, Kivekäs Ilkka, Willberg Tytti, Saarentaus Elmo, Toppila-Salmi Sanna, Dietz Aarno, Haapaniemi Teppo, Hytönen Vesa P, Toivola Sari, Palotie Aarno, Mäkitie Antti, Kettunen Johannes

Abstract excerpt

To evaluate the genetics of chronic nonsuppurative otitis media (OM). We performed a genome-wide association study of 429,599 individuals included in the FinnGen study using three different case definitions: combined chronic nonsuppurative OM (7034 cases) (included serous and mucous chronic OM), mucous chronic OM (5953 cases), and secretory chronic OM (1689 cases). Individuals without otitis media were used as...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 39112560
DOI: 10.1038/s41598-024-68781-1
PMCID: PMC11306868

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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