Article
The relation between depression and parkin genotype: the CORE-PD study.
Parkinsonism & related disorders - 1 Dec 2011
Srivastava A, Tang M-X, Mejia-Santana H, Rosado L, Louis E D, Caccappolo E, Comella C, Colcher A, Siderowf A, Jennings D, Nance M, Bressman S, Scott W K, Tanner C, Mickel S, Andrews H, Waters C, Fahn S, Cote L, Frucht S, Ford B, Alcalay R N, Ross B, Orbe Reilly M, Rezak M, Novak K, Friedman J H, Pfeiffer R D, Marsh L, Hiner B, Merle D, Ottman R, Clark L N, Marder K
Abstract excerpt
BACKGROUND: Mutations in parkin are a known genetic risk factor for early onset Parkinson's disease (EOPD) but their role in non-motor manifestations is not well established. Genetic factors for depression are similarly not well characterized. We investigate the role of parkin mutations in depression among those with EOPD and their relatives. METHODS: We collected psychiatric information using the Patient Health...
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