The relationship between obsessive-compulsive symptoms and PARKIN genotype: The CORE-PD study.

doi:10.1002/mds.26065

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Article

The relationship between obsessive-compulsive symptoms and PARKIN genotype: The CORE-PD study.

Movement disorders : official journal of the Movement Disorder Society - 1 Feb 2015

Sharp Madeleine E, Caccappolo Elise, Mejia-Santana Helen, Tang Ming-X, Rosado Llency, Orbe Reilly Martha, Ruiz Diana, Louis Elan D, Comella Cynthia, Nance Martha, Bressman Susan, Scott William K, Tanner Caroline, Waters Cheryl, Fahn Stanley, Cote Lucien, Ford Blair, Rezak Michael, Novak Kevin, Friedman Joseph H, Pfeiffer Ronald, Payami Haydeh, Molho Eric, Factor Stuart A, Nutt John, Serrano Carmen, Arroyo Maritza, Pauciulo Michael W, Nichols William C, Clark Lorraine N, Alcalay Roy N, Marder Karen S

Abstract excerpt

BACKGROUND: Few studies have systematically investigated the association between PARKIN genotype and psychiatric co-morbidities of Parkison's disease (PD). PARKIN-associated PD is characterized by severe nigral dopaminergic neuronal loss, a finding that may have implications for behaviors rooted in dopaminergic circuits such as obsessive-compulsive symptoms (OCS). METHODS: The Schedule of Compulsions and...

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PMID: 25393808
DOI: 10.1002/mds.26065
PMCID: PMC4318772

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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