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Investigating the Shared Genetic Etiology Between Parkinson's Disease and Depression.

Journal of Parkinson's disease - 1 Jan 2024

Reyes-Pérez Paula, García-Marín Luis M, Aman Asma M, Antar Tarek, Flores-Ocampo Victor, Mitchell Brittany L, Medina-Rivera Alejandra, Rentería Miguel E

Abstract excerpt

Background: Depression is a common symptom in Parkinson's disease (PD), resulting from underlying neuropathological processes and psychological factors. However, the extent to which shared genetic risk factors contribute to the relationship between depression and PD is poorly understood. Objective: To examine the effects of common genetic variants influencing the etiology of PD and depression risk at the...

Topics

Humans
Parkinson Disease
Genome-Wide Association Study
Depression
Mendelian Randomization Analysis
Genetic Predisposition to Disease
Linkage Disequilibrium
Polymorphism, Single Nucleotide

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Identifiers

PMID: 38457145
DOI: 10.3233/JPD-230176
PMCID: PMC11091633

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026.

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