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Article

Risk of Parkinson's disease and depression severity in different populations: A two-sample Mendelian randomization analysis.

Brain and behavior - 1 Sept 2024

Qin Yidan, Li Jia, Quan Wei, Song Jia, Xu Jing, Chen Jiajun

Abstract excerpt

BACKGROUND: Depression is widely recognized as a common non-motor symptom of Parkinson's disease (PD). Across different studies, the reported prevalence of depression in PD varies widely, ranging from 2.7% to 90%, but it is unclear whether this association is due to genetic or acquired factors. Whether there is a causal relationship remains unknown. The aim of this study was to use a two-sample Mendelian...

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Identifiers

PMID: 39219304
DOI: 10.1002/brb3.3642
PMCID: PMC11366827

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