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Article

Second-site revertants of the P1 copN22 copy mutant.

Journal of bacteriology - 1 May 1990

Froehlich B J, Scott J R

Abstract excerpt

Miniplasmids with the P1 copN22 mutation have a copy number about seven times that of the wild type. Selection for reduced copy number from this plasmid led to the isolation of second-site pseudorevertants, called poc mutants. DNA sequence analysis showed that all six independent poc mutants have a single base change in the same codon of the repA gene. This implicates the amino acid at this location, either...

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Identifiers

PMID: 2185232
DOI: 10.1128/jb.172.5.2762-2764.1990
PMCID: PMC208922

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