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Article

Cancer predisposition of ataxia-telangiectasia heterozygotes.

Cancer genetics and cytogenetics - 1 May 1990

Swift M, Chase C L, Morrell D

Abstract excerpt

Ataxia-telangiectasia (A-T) is a progressive neurologic disorder in which there is varied immune dysfunction, an excess sensitivity to ionizing radiation, and a striking predisposition to cancer. It is the autosomal recessive syndrome for which there is the strongest evidence, derived from retrospective studies of cancer incidence and mortality in A-T families, that the heterozygote is predisposed to cancer. We...

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PMID: 2184933
DOI: 10.1016/0165-4608(90)90004-t

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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