Cancer predisposition of ataxia-telangiectasia heterozygotes.

doi:10.1016/0165-4608(90)90004-t

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Article

Cancer predisposition of ataxia-telangiectasia heterozygotes.

Cancer genetics and cytogenetics - 1 May 1990

Swift M, Chase C L, Morrell D

Abstract excerpt

Ataxia-telangiectasia (A-T) is a progressive neurologic disorder in which there is varied immune dysfunction, an excess sensitivity to ionizing radiation, and a striking predisposition to cancer. It is the autosomal recessive syndrome for which there is the strongest evidence, derived from retros...

Topics

Ataxia Telangiectasia
Female
Genetic Predisposition to Disease
Heterozygote
Humans
Male
Neoplasms

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