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Article

ATM mutations in cancer families.

Cancer research - 15 Sept 1996

Vorechovský I, Luo L, Lindblom A, Negrini M, Webster A D, Croce C M, Hammarström L

Abstract excerpt

Ataxia-telangiectasia (A-T) is a multisystem recessive disease characterized clinically by cerebellar ataxia, oculocutaneous telangiectasias, immunodeficiency, sensitivity to radiomimetic agents, and cancer predisposition. This pleiotropic disorder is caused by mutations in the ATM (mutated in A-T) gene, which is located in the human chromosomal region 11q22-q23. The ATM gene product is a member of a novel family...

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Source

Identifiers

PMID: 8797579

Genes

ATM

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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ATM mutations in cancer families.PMID 8797579Read ↗

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ATM germline mutations in women with familial breast cancer and a relative with haematological malignancy.Semantic proximity Read ↗

Whole genome joint analysis reveals ATM:C.1564_1565del variant segregating with Ataxia-Telangiectasia and breast cancer.Semantic proximity Read ↗

Evaluation of the role of Finnish ataxia-telangiectasia mutations in hereditary predisposition to breast cancer.Semantic proximity Read ↗

Ataxia-telangiectasia gene (ATM) mutation heterozygosity in breast cancer: a narrative review.Semantic proximity Read ↗

ATM mutations that cause ataxia-telangiectasia are breast cancer susceptibility alleles.Semantic proximity Read ↗

Increased frequency of ATM mutations in breast carcinoma patients with early onset disease and positive family history.Semantic proximity Read ↗

Ataxia-Telangiectasia Mutated (ATM) gene signaling pathways in human cancers and their therapeutic implications.Semantic proximity Read ↗

Management of Individuals With a Mutation in the Ataxia Telangiectasia Mutated Gene.Semantic proximity Read ↗

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