Article

The development of a differential assay for the determination of ataxia-telangiectasia heterozygosity in human subjects

2008-01-01

Abstract excerpt

Ataxia-telagiectasia (A-T) patients exhibit increased sensitivity to ionising radiation and also demonstrate a higher than normal risk of developing cancer. Heterozygote phenotypes exhibit intermediate levels of radiation sensitivity compared to A-T homozygotes and controls and also have an increased risk of cancer, but are asymptomatic. Radiation used in diagnostic procedures could predispose such individuals to...

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Literature Corpus work: a7781194-7f16-551d-aa4c-ad5910422c2e
DOI: 10.25401/cardiffmet.20337705.v1

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