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Article

Synergistic associations of depression and apolipoprotein E genotype with incidence of dementia.

International journal of geriatric psychiatry - 1 Sept 2011

Kim Jae-Min, Stewart Robert, Kim Seon-Young, Kim Sung-Wan, Bae Kyung-Yeol, Yang Su-Jin, Shin Il-Seon, Yoon Jin-Sang

Abstract excerpt

OBJECTIVES: A cohort study of Japanese-American men suggested interactive effects of depression and apolipoprotein E (APOE) e4 allele on risk of incident dementia. In another sample of East Asian origin, we sought to replicate the findings and to explore individual depressive symptoms where this interaction was most evident. METHODS: Of 625 Korean community elders without dementia at baseline, 518 (83%) were...

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Source

Identifiers

PMID: 21845591
DOI: 10.1002/gps.2621

Genes

APOE

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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