Article
Genetic variation in the psychomotor stimulant properties of cocaine in Mus musculus.
Psychopharmacology - 1 May 2003
Downing Chris, Rodd-Henricks Kristina, Marley Rodney J, Dudek Bruce C
Abstract excerpt
RATIONALE: The psychomotor stimulant properties of drugs are argued to be a key feature of abuse liability. Several studies, primarily using inbred strains of mice, have demonstrated genetic variation in the psychomotor stimulant properties of cocaine. As of yet, however, no gene(s) has been identified which influences this phenotype. OBJECTIVES: The purpose of the present study was to examine a number of inbred...
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