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Article

Evidence of association between Val66Met polymorphism at BDNF gene and anxiety disorders in a community sample of children and adolescents.

Neuroscience letters - 20 Sept 2011

Tocchetto Andréa, Salum Giovanni A, Blaya Carolina, Teche Stefania, Isolan Luciano, Bortoluzzi Andressa, Rebelo E Silva Rafael, Becker Juliana A, Bianchin Marino M, Rohde Luis Augusto, Leistner-Segal Sandra, Manfro Gisele G

Abstract excerpt

Different lines of evidence support BDNF as a candidate gene in mood and anxiety modulation. More recently, the Met allele of the BDNF Val66Met polymorphism has been implicated in anxiety in animal models and anxiety-traits in humans. The aim of this study is to evaluate the a priori hypothesis that the association between anxiety disorders and Val66Met polymorphism at the BDNF gene would be replicated in a...

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Source

Identifiers

PMID: 21839144
DOI: 10.1016/j.neulet.2011.07.044

Genes

BDNF

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Evidence of association between Val66Met polymorphism at BDNF gene and anxiety disorders in a community sample of children and adolescents.PMID 21839144Read ↗

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The BDNF gene Val66Met polymorphism as a modifier of psychiatric disorder susceptibility: progress and controversy.Semantic proximity Read ↗

The Met allele of BDNF Val66Met polymorphism is associated with increased BDNF levels in generalized anxiety disorder.Semantic proximity Read ↗

BDNF variant linked to anxiety-related behaviors.Semantic proximity Read ↗

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The BDNF Val66Met polymorphism and anxiety: support for animal knock-in studies from a genetic association study in humans.Semantic proximity Read ↗

BDNF gene polymorphism (Val66Met) predicts amygdala and anterior hippocampus responses to emotional faces in anxious and depressed adolescents.Semantic proximity Read ↗

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