Article

EPAC1 regulates endothelial Annexin A2 cell surface translocation and plasminogen activation

2017-09-12

Abstract excerpt

<h4>ABSTRACT</h4> Annexins, a family of highly conserved calcium-and phospholipid-binding proteins, play important roles in a wide range of physiological functions. Among the twelve known annexins in human, Annexin A2 (AnxA2) is one of the most extensively studied and has been implicated in various human diseases. AnxA2 can exist as a monomer or a heterotetrameric complex with S100A10 (P11) and plays a critical r...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: e1d00454-a6b4-5b03-8966-c6930dd29a54
DOI: 10.1101/187559

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

EPAC1 regulates endothelial Annexin A2 cell surface translocation and plasminogen activationDOI 10.1101/187559Read

Research Progress of Annexin A1 and Its Derived Peptides in The Diagnosis and Treatment of Circulatory DiseasesSemantic proximity Read

Annexin A1 localization and its relevance to cancerSemantic proximity Read

Annexin A2 (ANX A2): An emerging biomarker and potential therapeutic target for aggressive cancersSemantic proximity Read

Association of annexin A2 with cancer development (Review)Semantic proximity Read

ANNEXIN A1: Roles in Placenta, Cell Survival, and NucleusSemantic proximity Read

Annexin A2: Its Molecular Regulation and Cellular Expression in Cancer DevelopmentSemantic proximity Read

EPAC regulates von Willebrand factor secretion from endothelial cells in a PI3K/eNOS-dependent manner during inflammationSemantic proximity Read

Annexin A2: biology and relevance to the antiphospholipid syndromeSemantic proximity Read

Annexin A2 is a natural extrahepatic inhibitor of the PCSK9-induced LDL receptor degradation.Semantic proximity Read

Molecular dissection of the membrane aggregation mechanisms induced by monomeric annexin A2.Semantic proximity Read

Prostaglandin-endoperoxide synthase-2 deletion affects the natural trafficking of Annexin A2 in monocytes and favours venous thrombosis in mice.Semantic proximity Read

Rab3D and annexin A2 play a role in regulated secretion of vWF, but not tPA, from endothelial cells.Semantic proximity Read