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Article

The Functional SNPs in the 5' Regulatory Region of the Porcine PPARD Gene Have Significant Association with Fat Deposition Traits.

PloS one - 1 Jan 2015

Zhang Yunxia, Gao Tengsen, Hu Shanyao, Lin Bin, Yan Dechao, Xu Zaiyan, Zhang Zijun, Mao Yuanliang, Mao Huimin, Wang Litong, Wang Guoshui, Xiong Yuanzhu, Zuo Bo

Abstract excerpt

Peroxisome proliferator-activated receptor delta (PPARD) is a key regulator of lipid metabolism, insulin sensitivity, cell proliferation and differentiation. In this study, we identified two Single Nucleotide Polymorphisms (SNPs, g.1015 A>G and g.1018 T>C) constituting four haplotypes (GT, GC, AC and AT) in the 5' regulatory region of porcine PPARD gene. Functional analysis of the four haplotypes showed that the...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 26599230
DOI: 10.1371/journal.pone.0143734
PMCID: PMC4658063

Genes

PPARD

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