Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Contribution of variants in and near the IRF6 gene to the risk of nonsyndromic cleft lip with or without cleft palate in a Malay population.

American journal of medical genetics. Part A - 1 Sept 2011

Salahshourifar Iman, Sulaiman Wan Azman Wan, Zilfalil Bin Alwi, Halim Ahmad Sukari

Abstract excerpt

Several studies have shown evidence for the contribution of interferon regulatory factor 6 (IRF6) variants to the risk of nonsyndromic oral clefts in Asians; however, this has not included the Malay population. The current study attempts to address this research gap using allele and haplotype transmission disequilibrium analyses. The results showed a strong transmission distortion for multiple haplotypes to...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Alleles
Share to Cleft Lip

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Cleft Palate

Share to Genetic Variation

Share to Haplotypes

Share to Interferon Regulatory Factors

Share to Linkage Disequilibrium

Share to Malaysia

Source

Identifiers

PMID: 21834040
DOI: 10.1002/ajmg.a.34169

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Contribution of variants in and near the IRF6 gene to the risk of nonsyndromic cleft lip with or without cleft palate in a Malay population.PMID 21834040Read ↗

Association between IRF6 and nonsyndromic cleft lip with or without cleft palate in four populations.Semantic proximity Read ↗

Association of single nucleotide polymorphisms in the IRF6 gene with nonsyndromic cleft lip with or without cleft palate in Kinh Vietnamese patients.Semantic proximity Read ↗

IRF6 rs2235371 as a risk factor for non-syndromic cleft palate only among the Deutero-Malay race in Indonesia and its effect on the IRF6 mRNA expression level.Semantic proximity Read ↗

Association between IRF6 SNPs and oral clefts in West China.Semantic proximity Read ↗

Association between interferon regulatory factor 6 gene polymorphisms and nonsyndromic cleft lip with or without cleft palate in a chinese population.Semantic proximity Read ↗

Association among IRF6 polymorphism, environmental factors, and nonsyndromic orofacial clefts in western china.Semantic proximity Read ↗

IRF6 polymorphisms are associated with nonsyndromic orofacial clefts in a Chinese Han population.Semantic proximity Read ↗

Association Between IRF6 Variants and Nonsyndromic Cleft Lip With or Without Cleft Palate in Chile.Semantic proximity Read ↗

Breakthroughs in the genetics of orofacial clefting.Semantic proximity Read ↗

Variation in IRF6 contributes to nonsyndromic cleft lip and palate.Semantic proximity Read ↗

The IRF6 rs2013162 and MTHFR A1298C rs1801131 Gene Polymorphisms Related to non-Syndromic Cleft lip and Palate among Deutero-Malay in Indonesia.Semantic proximity Read ↗

IRF6 is a risk factor for nonsyndromic cleft lip in the Brazilian population.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.