Article
IRF6 rs2235371 as a risk factor for non-syndromic cleft palate only among the Deutero-Malay race in Indonesia and its effect on the IRF6 mRNA expression level.
Dental and medical problems - 1 Jan 2000
Nasroen Saskia Lenggogeni, Maskoen Ani Melani, Soedjana Hardisiswo, Hilmanto Dany, Gani Basri Abdul
Abstract excerpt
BACKGROUND: During the early embryological development of the face, complex orofacial failure results in a non-syndromic cleft lip and palate (NS CLP). The interferon regulatory factor 6 gene (IRF6) rs2235371 is a non-synonymous polymorphism that is one of the strong candidate genes associated with NS CLP. OBJECTIVES: The purpose of this study was to determine IRF6 rs2235371 as a risk factor for NS CLP and its...
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