Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Isolation of mutant Saccharomyces cerevisiae strains that survive without sphingolipids.

Molecular and cellular biology - 1 May 1990

Dickson R C, Wells G B, Schmidt A, Lester R L

Abstract excerpt

Sphingolipids comprise a large, widespread family of complex eucaryotic-membrane constituents of poorly defined function. The yeast Saccharomyces cerevisiae is particularly suited for studies of sphingolipid function because it contains a small number of sphingolipids and is amenable to molecular genetic analysis. Moreover, it is the only eucaryote in which mutants blocked in sphingolipid biosynthesis have been...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Blotting, Southern
Share to DNA, Fungal
Share to Fatty Acids

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Inositol

Share to Mutation

Share to Saccharomyces cerevisiae

Share to Suppression, Genetic

Source

Open in PubMed Open full text

Identifiers

PMID: 2183021
DOI: 10.1128/mcb.10.5.2176-2181.1990
PMCID: PMC360565

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Isolation of mutant Saccharomyces cerevisiae strains that survive without sphingolipids.PMID 2183021Read ↗

The yeast sphingolipid signaling landscape.Semantic proximity Read ↗

Mutant strains of Saccharomyces cerevisiae lacking sphingolipids synthesize novel inositol glycerophospholipids that mimic sphingolipid structures.Semantic proximity Read ↗

Metabolism and selected functions of sphingolipids in the yeast Saccharomyces cerevisiae.Semantic proximity Read ↗

Phenotypes of sphingolipid-dependent strains of Saccharomyces cerevisiae.Semantic proximity Read ↗

Strategies for generating phospholipid synthesis mutants in yeast.Semantic proximity Read ↗

Identification of a Saccharomyces gene, LCB3, necessary for incorporation of exogenous long chain bases into sphingolipids.Semantic proximity Read ↗

Dominant suppressor mutation bypasses the sphingolipid requirement for growth of Saccharomyces cells at low pH: role of the CWP2 gene.Semantic proximity Read ↗

Large scale deletions in the Saccharomyces cerevisiae genome create strains with altered regulation of carbon metabolism.Semantic proximity Read ↗

Studying phospholipid metabolism using yeast systematic and chemical genetics.Semantic proximity Read ↗

A genomewide screen reveals a role of mitochondria in anaerobic uptake of sterols in yeast.Semantic proximity Read ↗

Serine-Dependent Sphingolipid Synthesis Is a Metabolic Liability of Aneuploid CellsSemantic proximity Read ↗

Impairment of ribosomes and DNA biosynthesis confers resistance to Inhibition of sphingolipid biosynthesis.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.