Article
Isolation of mutant Saccharomyces cerevisiae strains that survive without sphingolipids.
Molecular and cellular biology - 1 May 1990
Dickson R C, Wells G B, Schmidt A, Lester R L
Abstract excerpt
Sphingolipids comprise a large, widespread family of complex eucaryotic-membrane constituents of poorly defined function. The yeast Saccharomyces cerevisiae is particularly suited for studies of sphingolipid function because it contains a small number of sphingolipids and is amenable to molecular genetic analysis. Moreover, it is the only eucaryote in which mutants blocked in sphingolipid biosynthesis have been...
Topics
- Blotting, Southern
- DNA, Fungal
- Fatty Acids
- Inositol
- Mutation
- Saccharomyces cerevisiae
- Sphingolipids
- Suppression, Genetic