Mutant strains of Saccharomyces cerevisiae lacking sphingolipids synthesize novel inositol glycerophospholipids that mimic sphingolipid structures.

Article

Mutant strains of Saccharomyces cerevisiae lacking sphingolipids synthesize novel inositol glycerophospholipids that mimic sphingolipid structures.

The Journal of biological chemistry - 15 Jan 1993

Lester R L, Wells G B, Oxford G, Dickson R C

Abstract excerpt

Mutant strains of Saccharomyces cerevisiae, termed SLC, make no detectable sphingolipids when cultured without a sphingolipid long chain base such as phytosphingosine (Dickson, R.C., Wells, G.B., Schmidt, A., and Lester, R.L. (1990) Mol. Cell. Biol. 10, 2176-2181). When grown with phytosphingosin...

Topics

Chromatography, High Pressure Liquid
Fatty Acids
Inositol
Molecular Structure
Mutation
Phosphatidylinositols
Saccharomyces cerevisiae
Sphingolipids

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