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Article

Genetic polymorphism of CYP4A11 and CYP4A22 genes and in silico insights from comparative 3D modelling in a French population.

Gene - 1 Nov 2011

Lino Cardenas Christian L, Renault Nicolas, Farce Amaury, Cauffiez Christelle, Allorge Delphine, Lo-Guidice Jean-Marc, Lhermitte Michel, Chavatte Philippe, Broly Franck, Chevalier Dany

Abstract excerpt

The CYP4A subfamily is known to ω-hydroxylate the endogenous arachidonic acid into 20-hydroxyeicosatetranoic acid, which has renovascular and tubular functions. The aim of this work was to report a comprehensive investigation of the CYP4A11 and CYP4A22 genetic polymorphisms in a French population. Using PCR-SSCP and sequencing strategies, a total of 26 sequence variations were identified comprising 3 missense...

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Identifiers

PMID: 21820496
DOI: 10.1016/j.gene.2011.07.015

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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