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Article

Arachidonic acid ω-hydroxylase CYP4A11: inter-ethnic variations in the 8590T>C loss-of-function variant.

Molecular biology reports - 1 Feb 2012

Lino Cardenas Christian Lacks, Devos Aurore, Toure Aminata, Cardenas Garcia Jaime, Kenani Abderraouf, Migot-Nabias Florence, Broly Franck, Chevalier Dany

Abstract excerpt

The human Cytochrome P450 4A11 (CYP4A11) is a major ω-hydroxylase involved in the regulation of blood pressure in the kidney through the conversion of arachidonic acid into 20-hydroxyeicosatetraenoic acid (20-HETE). Previous studies have reported a significant association between the 8590T>C genetic variant of CYP4A11 and hypertension. Interestingly, several population-based studies have reported ethnic...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 21617944
DOI: 10.1007/s11033-011-0888-x

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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