Article
Applicability of a genetic signature for enhanced iloperidone efficacy in the treatment of schizophrenia.
The Journal of clinical psychiatry - 1 Jun 2009
Volpi Simona, Potkin Steven G, Malhotra Anil K, Licamele Louis, Lavedan Christian
Abstract excerpt
OBJECTIVE: To demonstrate how several polymorphisms previously associated with the efficacy of the novel antipsychotic iloperidone could be used together to predict clinical response and provide practical information for individualized treatment. METHOD: This inpatient randomized, double-blind, placebo- and ziprasidone-controlled, 28-day study of the efficacy of iloperidone was conducted from November 2005 to...
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